David Gonilski-Pacin
Postdoctoral Researcher · Cell & Molecular Biology
Wachten Lab, Institute of Innate Immunity
University Hospital Bonn (UKB) · University of Bonn
ImmunoSensation² Cluster of Excellence
Bonn, Germany
"Cell biologist studying ciliary signaling and epithelial–immune crosstalk in kidney disease."
Research
Ciliary cAMP signaling, renal epithelial–macrophage crosstalk and the secretome in autosomal dominant polycystic kidney disease (ADPKD). Previous doctoral work on RSUME/AURKA and primary cilia in clear cell renal cell carcinoma (ccRCC).
Topics
Techniques
Publications
New insights in cellular senescence: The pituitary model.
J Neuroendocrinol. 2025;37(5):e70008
DOI: 10.1111/jne.70008The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway.
Aging Cell. 2024;23(10):e14258
DOI: 10.1111/acel.14258Expression of RSUME is Associated With Poor Prognosis in Clear Cell Renal Carcinoma: Involvement of ROS Related Metabolism.
Clin Genitourin Cancer. 2023;21(3):393–402.e5
DOI: 10.1016/j.clgc.2023.03.008Role of RSUME in inflammation and cancer.
Front Endocrinol (Lausanne). 2022;13:864780
DOI: 10.3389/fendo.2022.864780Mass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism.
J Proteome Res. 2021;20(1):786–803
DOI: 10.1021/acs.jproteome.0c00655von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME.
Cell Death Dis. 2019;10(4):266
DOI: 10.1038/s41419-019-1507-3Education
Ph.D. in Biological Sciences 2019–2025
University of Buenos Aires (UBA) · Research at IBioBA – CONICET / Max Planck Partner Institute
Advisor: Prof. Eduardo Arzt · RSUME / AURKA and primary cilia in clear cell renal cell carcinoma (ccRCC) in the context of von Hippel–Lindau (VHL) syndrome
Statistical Analysis of Genome Scale Data 2023 Course
Cold Spring Harbor Laboratory (CSHL)
Licenciatura in Biological Sciences 2013–2019
University of Buenos Aires (UBA)
Bachelor’s + integrated Master’s-level degree · specialization in Molecular Biology
Teaching
Chief of Practical Applications 2021–2023
Universidad Nacional de José Clemente Paz (UNPAZ)
Courses: Biostatistics & Demography; Microbiology & Parasitology
Teaching Assistant 2019–2021
Facultad de Ciencias Exactas y Naturales (FCEN), UBA
Courses: Introduction to Bioinformatics · Biological Chemistry · Genetics I · Industrial Biology and Applied Microbiology (BIMA)
Paid position obtained through public contest
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